
Introduction: Why One-Size-Fits-All Doesn’t Work in Starving Cancer
In the last installment of our three-part series on Jane McLelland’s phenomenal book on starving cancer, we explore her personalized approach to cancer treatment.
Jane has concluded that cancer doesn’t play by the same rules for everyone, so why should our treatments? That’s the heart of Jane McLelland’s approach—personalization. She believes that to truly starve cancer, we need to understand its unique metabolism and tailor our strategies accordingly. It’s like customizing a diet plan or a workout routine, but for fighting cancer. Let’s break it down.
Understanding Your Cancer’s Metabolic Phenotype to Starve It
First things first, we need to figure out what makes your cancer tick. Every cancer has its own metabolic phenotype—medical terminology for the specific fuel sources and pathways it uses. Some cancers are sugar fiends, others thrive on fat, and some are a mix of both.
Jane’s metro map is a great tool for this. It’s like a cheat sheet that shows all the pathways cancer cells use to get their fuel. By analyzing your cancer’s unique characteristics, you can identify which pathways to target. There are even online tools and databases that can help with this. It’s like detective work, but for your health and for starving cancer.
Diet and Lifestyle: Fueling the Fight to Starve Cancer
Now, let’s talk about diet. You’ve probably heard about ketogenic diets for cancer, right? However, Jane has a different perspective. She doesn’t believe in a one-size-fits-all diet. Instead, she recommends tailoring your diet to your cancer’s specific needs.
For example, if your cancer loves sugar, you might want to try intermittent fasting or a fasting-mimicking diet to reduce glucose availability. But if your cancer is more into fat, a strict keto diet might backfire by pushing it to adapt. The key is to be flexible and work with your body, not against it, to starve cancer effectively.
Combination Therapy: Blocking Multiple Pathways to Starve Cancer

Here’s where things get really exciting. Jane’s approach is all about combining therapies to create a powerful, multi-pronged attack. She calls this “synthetic lethality”—where the combined effect of treatments is greater than the sum of their parts.
For example, you might pair mebendazole with metformin (to lower blood sugar) and statins (to disrupt fat pathways). This combo can starve cancer on multiple fronts, making it harder for the cells to adapt. It’s like surrounding the enemy and cutting off all their escape routes.
Challenges and Future Directions in Starving Cancer
To be honest, this approach isn’t without its challenges. For one, there’s a lack of randomized clinical trials (RCTs) for many of these repurposed drugs. Most of the evidence is anecdotal or based on preclinical studies. This highlights the need for further research.
Another challenge is cost and accessibility. Personalized treatment can be expensive, and not all doctors are familiar with cancer metabolism. But Jane is working to change that. She’s created a list of practitioners on her website who understand her approach, and she’s encouraging patients to share their experiences to refine treatment strategies for starving cancer.
Conclusion: Taking Control of Your Cancer Journey to Starve Cancer

Here’s the heart of it: Jane McLelland’s approach puts you in the driver’s seat. It’s about taking control of your cancer journey and using every tool at your disposal to fight back. By understanding your cancer’s unique metabolism and combining therapies like mebendazole, dietary changes, and off-label drugs, you can work toward starving cancer and improving your chances of success.
It’s not easy, and it’s not a quick fix. But it’s a new way of thinking about cancer treatment—one that’s personalized, proactive, and full of hope. If you’re interested in exploring this approach further, consult with a practitioner familiar with Jane’s methods and take the first step toward a tailored, effective plan to help you starve your cancer.
You’ve got this. Let’s starve cancer together.
To read the first of this series, click here. You can read the second part here.
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